Background Scientific Papers

Evaluation of equine immunoglobulin specific for Rhodococcus equi virulence-associated proteins A and C for use in protecting foals against Rhodococcus equi-induced pneumonia.

K.E. Hooper-McGrevy, S. Giguere, B.N. Wilkie, J.F. Prescott. AJVR, Vol 62, No. 8, August 2001.

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Prognostic value of clinicopathological variables obtained at admission and effect of antiendotoxin plasma on survival in septic and critically ill foals.

S.F. Peek, S. Semrad, S.M. McGuirk, A. Riseberg, J.A. Slack, F. Marques, D. Coombs, L. Lien, N. Keuler, B.J. Darien. J Vet Intern Med. 20: 569-574. 2006.

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Protection against clinical endotoxemia in horses by using plasma containing antibody to an Rc mutant E. coli (J5).

S.J. Spier, J-P. Lavole, J.S. Cullor, B.P. Smith, J.R. Snyder, W.M. Sischo. Circ Shock. 28: 235-248. 1989.

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Failure of Passive Transfer

Failure of Passive Transfer in foals: incidence and outcome on four studs in New South Wales

CM Tyler-McGowan, JL Hodgson and DR Hodgson, Aust Vet J 75: 56-59. 1997.

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Storage and Stability of Plasma and its Components

Coagulation parameters of thawed fresh-frozen plasma during storage at different temperatures

M Lamboo, DCW Poland, JCJ Eikenboom, MS Harvey, E Groot, A Brand, and RRP De Vries. Transfusion Medicine 17: 182-186, 2007.

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Vitamin K-dependent coagulation factors and fibrinogen levels in FFP remain stable upon repeated freezing and thawing.

O Ben-Tal, E Zwang, R Eichel, T Badalbev and M Hareuveni. Transfusion, Volume 43: 873-877.

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Serum biobank certification and the establishment of quality controls for biological fluids: examples of serum biomarker stability after temperature variation.

C Chaigneau, T Cabioch and F Betsou. Clin Chem Lab Med. 45(10): 1390-1395. 2007.

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Half-Lives of Immunoglobulins IgG, IgA and IgM in the serum of New-Born Pigs.

J Curtis and FJ Bourne. Immunology 24: 147-155. 1973.

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Indications for use of Plasma, Especially in Cases of Endotoxaemia

Current usage of intravenous immune globulin and the rationale behind it: the Massachusetts General Hospital data and a review of the literature.

K Darabi, O Abdel-Wahab, and WH Dzik. Transfusion 46: 741-753. 2006

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Clinical trials in spontaneous disease in dogs: a new paradigm for investigations of sepsis.

CM Otto. Journal of Veterinary Emergency and Critical Care. 17: 359-367. 2007.

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Endotoxin, cytokines and lipid peroxides in children with intussusception.

IE Willetts, P Kite, GR Barclay, RE Banks, A Rumley, V Allgar and MD Stringer. British Journal of Surgery. 88: 878-883. 2001.

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A Study of Intestinal Permeability in Relation to the Inflammatory Response and Plasma Endocab IgM Levels in Patients with Acute Pancreatitis.

JC Penalva, J Martinez, R Laveda, A Esteban, C Munoz, J Saez, J Such, S Navarro, F Feu, J Sanchez-Paya and M Parez-Mateo. J Clin Gastroenterology. 38: 512-517. July 2004.

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Endotoxaemia and cytokine production in experimental colitis.

PJD Neilly, KR Gardiner, SJ Kirk, G Jennings, NH Anderson, M Elia and BJ Rowlands. British Journal of Surgery 82: 1479-1482. 1995.

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Natural Cytokine Antagonists and Endogenous Antiendotoxin Core Antibodies in Sepsis Syndrome.

AS Goldie, KC Fearon, JA Ross, GR Barclay, RE Jackson, IS Grant, G Ramsay, AS Blyth and JC Howle. Journal of the American Medical association 274: 172-177. 12 July 1995.

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Indications for use of Plasma, Especially in Cases of Endotoxaemia in Horses

Equine Endotoxaemia – a state-of-the-art review of therapy.

BO Sykes and MO Furr. Aust Vet J 83: 45-50. 2005.

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Protection Against Clinical Endotoxaemia in Horses by Using Plasma Containing Antibody to an Rc Mutant E coli (J5).

SJ Spier, J-P Lavole, JS Cullor, BP Smith, JR Snyder and WM Sischo. Circulatory Shock 28: 235-248. 1989.

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Indications for use of Plasma in the Management of Rhodococcus Equi Infection in Foals

Necrotic Death of Rhodococcus Equi - Infected Macrophages is Regulated by Virulence-Associated Plasmids.

A Luhrmann, N Mauder, T Sydor, E Fernandez-Mora, J Schulze-Luehrmann, S Takai and A Haas. Infection and Immunity 72: 853-862. 2004.

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Identification of Pulmonary T-Lymphocyte and Serum Antibody Isotype Responses Associated with Protection against Rhodococcus Equi.

AM Lopez, MT Hines, GH Palmer, DC Alperin and SA Hines. Clinical and Diagnostic Laboratory Immunology 9: 1270-1276. 2002.

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Epidemiology of Rhodococcus Equi Infections: A Review.

S Takai. Veterinary Microbiology 56: 167-176. 1997.

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Immunity to Rhodococcus Equi.

SA Hines, ST Kanaly, BA Byrne and GH Palmer. Veterinary Microbiology 56: 177-185. 1997.

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